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isoniazid
noun
iso·ni·a·zid
ˌī-sə-ˈnī-ə-zəd
: a crystalline compound C6H7N3O used in treating tuberculosis
Examples of isoniazid in a Sentence
Recent Examples on the Web
Two medications used to treat tuberculosis, isoniazid and pyrazinamide, are known to interfere with how your body converts some tryptophan to niacin.
—Brittany Lubeck, Ms, Rdn, Verywell Health, 1 Aug. 2024
Examples include digoxin, chlorpromazine, and isoniazid.
—Sara Hoffman, Pharmd, Verywell Health, 2 July 2024
But most importantly, when an effective treatment became available, it was disseminated worldwide, and part of that happened because isoniazid was unpatentable, so costs for producing it and treating people with it remained low.
—Brianne Kane, Scientific American, 17 Oct. 2023
In this fashion, certain derivatives of hydrazine were discovered to be effective against Mycobacterium tuberculosis infection in mice, including the famous drug isoniazid, which is still used to this day as part of the standard treatment regimen for the lung infection.
—Rebecca Kreston, Discover Magazine, 27 Jan. 2016
Note:To be specific, XDR-TB is resistant to the two first-line drugs, isoniazid and rifampin, used to treat TB initially, plus any fluoroquinolone and at least one of three injectable second-line drugs (i.e., amikacin, kanamycin, or capreomycin).
—Rebecca Kreston, Discover Magazine, 7 Mar. 2013
Apolisi, together with a physician colleague, ensures that children in close contact with her TB patients take the daily preventive medication isoniazid for at least six months, as recommended by the WHO.
—Sofia Moutinho, Scientific American, 14 May 2022
Extensively drug-resistant TB (XDR-TB) is a form of MDR-TB that is resistant to isoniazid and rifampin, in addition to fluoroquinolones and injectable second-line drugs.
—Cnn Editorial Research, CNN, 6 June 2021
In the past decade, scientists have come up with two shorter courses: a drug called rifampin taken every day for four months; or a combination of isoniazid and rifapentine, taken once weekly for three months.
—Apoorva Mandavilli, New York Times, 23 Sep. 2019
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Word History
Etymology
is- + nicotinic acid + hydrazide
First Known Use
1952, in the meaning defined above
Dictionary Entries Near isoniazid
Cite this Entry
“Isoniazid.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/isoniazid. Accessed 10 Nov. 2024.
Medical Definition
isoniazid
noun
iso·ni·a·zid
ˌī-sə-ˈnī-ə-zəd
: a crystalline compound C6H7N3O used in treating tuberculosis
called also isonicotinic acid hydrazide
More from Merriam-Webster on isoniazid
Britannica.com: Encyclopedia article about isoniazid
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